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KMID : 1005220190340020070
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Journal of Embryo Transfer
2019 Volume.34 No. 2 p.70 ~ p.74
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The Potential of Renal Progenitor Cells in Kidney Diseases: Preclinical Findings
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Jo Jeong-Hyun
Kim Ki-Hoon
Kim Tae-Min
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Abstract
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The kidney is a highly complex organ, and acute or chronic renal diseases can occur with various complications such as diabetes and hypertension. So far, no target specific treatment is available in acute or chronic renal failure, necessitating the development of alternative therapeutic strategy. Recent experimental findings suggest that the renal function and structure can be restored after being treated with various sources of stem/progenitor cells. In this review, we discuss up-to-date findings of the potential of renal progenitor/stem cells in alleviating renal injuries with a focus on preclinical studies. We also review cellular mechanisms underlying the therapeutic function of these cells.
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KEYWORD
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kidney, progenitors, regeneration
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